Endocrine Abstracts

Introduction: ROHHADNET syndrome is a newly described condition characterized by rapid-onset obesity, pulmonary hypoventilation, hythalamic, autonomic dysregulation and, neural tumors. The severity of the clinical manifestations can rapidly lead to death by cardiorespiratory arrest.Case report: We present the case of a 5.10 years old girl, who was admitted in the Endocrinology department for evaluation of a significant weight gain began 2.5 years ago.</p...

Introduction: Parathyroid cyst is a very rare abnormality, representing 0.6% of all thyroid and parathyroid lesions. The diagnosis can be made on the basis of sonography and analysis of aspirated cystic fluid for parathyroid hormone. Parathyroid cysts are divided in two groups: functional (associated with clinical hyperparathyroidism) and non-functional. In the case of non-functional parathyroid cysts, fine needle aspiration is the elective treatment, but for functional parath...

Hirsutism may be the expression of hyperandrogenia of ovarian or adrenal origin, iatrogenic or idiopathic/familial. Regardless of the etiology, there is a negative impact of body hair excess on the self-image, the self-esteem and the sexual satisfaction of subjects. The present study aimed to evaluate 60 women, aged 26.3 years, with hirsutism as the primary symptom. At presentation, basal FSH, LH and testosterone levels, urinary 24-hours 17-ketosteroids and DHEA, and an abdomi...

Introduction: Recent data indicate that women affected by the polycystic ovary syndrome (PCOS) are at a greater risk for cardiovascular disease (CVD). The objective of this study was to evaluate the effect of the association ethinylestradiol 30 μg–drospirenone 3 mg (DRP/EE30 μg) plus metformin and weight loss on surrogate markers of CVD in PCOS.Methods: Twenty-five young women with PCOS (mean age 22.76±0.83 years, body mass index (BMI...

During the past thirty years bone biopsy has been used as an invasive diagnostic and research investigation of bone structure and metabolism. Bone biopsy parameters are used to assess both bone mass and bone quality. This study aimed to establish the value of routine qualitative bone biopsy evaluation in subjects with unclear primary osteoporosis. One-hundred seventy patients (73 men and 97 women), aged 54.29±0.95 years, were included in the study. The diagnosis was based...

Aim: The aim of our study was to assess the presence of endothelial dysfunction and of increased carotid intimae-media thickness (IMT), two precocious markers of atherosclerosis in PCOS subjects. Simultaneously, their relationship with some metabolic, hormonal and anthropometric parameters was analyzed.Methods: The study group consisted of 45 women with PCOS (age=23.1±4.1 years, body mass index (BMI) =28.4±5.9 kg/m2). Thirty-two heal...